Why do some men start losing their hair at 30, others at 50, and some not at all? The answer usually lies in genetics and hormones, specifically DHT.
The abbreviation DHT is often mentioned in discussions and articles about hair loss, but what exactly is it?
DHT, or dihydrotestosterone, is a male hormone closely linked to hereditary hair loss (also known as androgenetic alopecia). This also affects women, as they have testosterone too, although at much lower levels, and the pattern of hair loss differs. Typically, this is related to menopause when hormonal balance shifts.
DHT is an androgen (male hormone), just like testosterone, but with a much stronger binding affinity to hair follicle receptors, making it more harmful. This means that if you have genetic factors for androgenetic hair loss, you are more sensitive to DHT, which causes a faster process of hair miniaturisation (the hair follicle shrinks and produces smaller, lighter hairs).
When the hair follicle remains in the resting phase for a long time, the skin grows over the follicle (scarring), causing the follicle to atrophy, leaving the area bald. Once scarring occurs, hair growth cannot be restored, so it is important to try to prevent hair loss before scarring takes place.
Testosterone is converted to a more potent androgen, 5α-dihydrotestosterone (DHT), through the enzyme 5α-reductase. DHT and testosterone bind to hair follicle receptors, causing changes in hair growth that lead to hair miniaturisation.
The complete mechanism of androgenetic hair loss is not yet fully understood. However, we can at least reduce the conversion of testosterone into DHT by inhibiting the 5α-reductase enzyme (DHT blocker) and prevent DHT from binding to hair follicle receptors.
This can be done with medications, but they often come with well-known side effects. We believe safer inhibitors are needed than those currently licensed. With years of experience in hair loss, we have developed the natural TR2 and TR3 treatment serums based on proven scientific results.
